How much does Zofran cost without insurance?

The typical retail price for Zofran (ondansetron) is approximately $80 per month. Mark Cuban Cost Plus Drugs offers it for $4/mo.

Is there a generic for Zofran?

Yes, generic ondansetron is available (since 2006) and typically costs $12 per month.

Zofran (ondansetron) — Savings Options

Anti-Nausea · Last verified 2026-03-22

Current Pricing

Retail Price

$80

per month (estimated)

Cost Plus Drugs

Mark Cuban Cost Plus Drugs

Generic Price

$12

generic ondansetron (since 2006)

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Key Facts

Category: Anti-Nausea
Generic Name: ondansetron
Dosages: 4mg, 8mg
Generic Available: Yes (since 2006)
Typical Quantity: 12 units/mo

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